Identity and labeled form
SLU-PP-332 is a synthetic small-molecule agonist of estrogen-related receptors ERR-alpha, ERR-beta and ERR-gamma. It is not a peptide. The prepared product is labeled 20 mg per tablet in a 100-tablet bottle; that form and pack statement is not an administration recommendation.
Primary mechanism and mouse experiments
Billon et al. (2023) describe receptor and transcriptional experiments and an ERR-alpha-dependent exercise-associated response in mouse skeletal muscle. Their paper also reports mouse exercise-capacity observations.
Billon et al. (2024) studied a synthetic ERR agonist in obese-mouse metabolic models. These mouse endpoints should not be described as human exercise or weight-management benefits.
Chemical optimization
Okda et al. (2026) report chemical optimization and characterization of SLU-PP-332 analogues, with experimental and computational work on ERR signaling. Findings for an optimized analogue must not automatically be assigned to unchanged SLU-PP-332.
Limitations
The cited primary work concerns cells, chemistry and rodent models. It does not establish a human-use protocol, tablet bioavailability or the contents of the prepared bottle. Chemical identity, labeled form and exact lot evidence remain separate from the research findings.
Related
- slu pp 332 20mg 100 tabletsproduct
References
- Billon C et al. (2023). Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity. [primary; receptor/transcriptional experiments and mice]PMID: 36988910DOI: 10.1021/acschembio.2c00720
- Billon C et al. (2024). A Synthetic ERR Agonist Alleviates Metabolic Syndrome. [primary; obese-mouse metabolic models]PMID: 37739806DOI: 10.1124/jpet.123.001733
- Okda HE et al. (2026). Chemical optimization of the exercise mimetic SLU-PP-332 enables insight into estrogen-related receptor signaling. [primary; analogue chemistry and experimental/computational ERR characterization]PMID: 41850449DOI: 10.1016/j.ijbiomac.2026.151450
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